Transgenic cows that produce recombinant human lactoferrin in milk are not protected from experimental Escherichia coli intramammary infection.

@article{Hyvnen2006TransgenicCT,
  title={Transgenic cows that produce recombinant human lactoferrin in milk are not protected from experimental Escherichia coli intramammary infection.},
  author={Paula Hyv{\"o}nen and Leena Suojala and Toomas Orro and Johanna Haaranen and Outi Simola and Christine Maria R\ontved and Satu Py{\"o}r{\"a}l{\"a}},
  journal={Infection and immunity},
  year={2006},
  volume={74 11},
  pages={6206-12}
}
This is the first study describing an experimental mastitis model using transgenic cows expressing recombinant human lactoferrin (rhLf) in their milk. The aim of the study was to investigate the concentrations in milk and protective effects of bovine and recombinant human lactoferrin in experimental Escherichia coli mastitis. Experimental intramammary infection was induced in one udder quarter of seven first-lactating rhLf-transgenic cows and six normal cows, using an E. coli strain isolated… CONTINUE READING

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Lactoferrin: a modulator of immune and inflammatory responses

  • D. Legrand, E. Elass, M. Carpentier, J. Mazurier
  • Cell Mol. Life Sci
  • 2005

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