Transgenic Wheat Expressing a Barley UDP-Glucosyltransferase Detoxifies Deoxynivalenol and Provides High Levels of Resistance to Fusarium graminearum.

@article{Li2015TransgenicWE,
  title={Transgenic Wheat Expressing a Barley UDP-Glucosyltransferase Detoxifies Deoxynivalenol and Provides High Levels of Resistance to Fusarium graminearum.},
  author={Xin Li and Sanghyun Shin and Shane Heinen and Ruth Dill-Macky and Franz Berthiller and Natalya Nersesian and Thomas E Clemente and Susan P McCormick and Gary J Muehlbauer},
  journal={Molecular plant-microbe interactions : MPMI},
  year={2015},
  volume={28 11},
  pages={1237-46}
}
Fusarium head blight (FHB), mainly caused by Fusarium graminearum, is a devastating disease of wheat that results in economic losses worldwide. During infection, F. graminearum produces trichothecene mycotoxins, including deoxynivalenol (DON), that increase fungal virulence and reduce grain quality. Transgenic wheat expressing a barley UDP-glucosyltransferase (HvUGT13248) were developed and evaluated for FHB resistance, DON accumulation, and the ability to metabolize DON to the less toxic DON-3… CONTINUE READING
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