Transgenic Overexpression of Tissue‐Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification

Abstract

BACKGROUND Ectopic vascular calcification is a common condition associated with aging, atherosclerosis, diabetes, and/or chronic kidney disease. Smooth muscle cells are the best characterized source of osteogenic progenitors in the vasculature; however, recent studies suggest that cells of endothelial origin can also promote calcification. To test this, we… (More)
DOI: 10.1161/JAHA.115.002499

Topics

Statistics

010020020162017
Citations per Year

Citation Velocity: 28

Averaging 28 citations per year over the last 2 years.

Learn more about how we calculate this metric in our FAQ.

Cite this paper

@inproceedings{Savinov2015TransgenicOO, title={Transgenic Overexpression of Tissue‐Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification}, author={Alexei Y Savinov and Maryam Salehi and Manisha C. Yadav and Ilian A Radichev and Jos{\'e} Luis Mill{\'a}n and Olga V Savinova}, booktitle={Journal of the American Heart Association}, year={2015} }