Transgenic Hydra allow in vivo tracking of individual stem cells during morphogenesis.

  title={Transgenic Hydra allow in vivo tracking of individual stem cells during morphogenesis.},
  author={J{\"o}rg Wittlieb and Konstantin Khalturin and Jan U Lohmann and Friederike Anton-Erxleben and Thomas C G Bosch},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={103 16},
Understanding the evolution of development in large part relies on the study of phylogenetically old organisms. Cnidarians, such as Hydra, have become attractive model organisms for these studies. However, despite long-term efforts, stably transgenic animals could not be generated, severely limiting the functional analysis of genes. Here we report the efficient generation of transgenic Hydra lines by embryo microinjection. One of these transgenic lines expressing EGFP revealed remarkably high… CONTINUE READING
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Development (Cambridge, U.K

  • M. Broun, H. R. Bode
  • 2002
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