Transgenesis of schistosomes: approaches employing mobile genetic elements.

  title={Transgenesis of schistosomes: approaches employing mobile genetic elements.},
  author={Victoria H Mann and Maria Elena Morales and Kristine J. Kines and Paul J. Brindley},
  volume={135 2},
Draft genome sequences for Schistosoma mansoni and Schistosoma japonicum are now available. However, the identity and importance of most schistosome genes have yet to be determined. Recently, progress has been made towards the genetic manipulation and transgenesis of schistosomes. Both loss-of-function and gain-of-function approaches appear to be feasible in schistosomes based on findings described in the past 5 years. This review focuses on reports of schistosome transgenesis, specifically… CONTINUE READING

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