Transgenerational phenotype aggravation in CAF-1 mutants reveals parent-of-origin specific epigenetic inheritance.

@article{Mozgov2018TransgenerationalPA,
  title={Transgenerational phenotype aggravation in CAF-1 mutants reveals parent-of-origin specific epigenetic inheritance.},
  author={Iva Mozgov{\'a} and Thomas Wildhaber and Minerva S Trejo-Arellano and Jiř{\'i} Fajkus and Pawel Roszak and Claudia K{\"o}hler and Lars Hennig},
  journal={The New phytologist},
  year={2018},
  volume={220 3},
  pages={
          908-921
        }
}
Chromatin is assembled by histone chaperones such as chromatin assembly factor CAF-1. We had noticed that vigor of Arabidopsis thaliana CAF-1 mutants decreased over several generations. Because changes in mutant phenotype severity over generations are unusual, we asked how repeated selfing of Arabidopsis CAF-1 mutants affects phenotype severity. CAF-1 mutant plants of various generations were grown, and developmental phenotypes, transcriptomes and DNA cytosine-methylation profiles were compared… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 69 REFERENCES

Identification of genes preventing transgenerational transmission of stress - induced epigenetic states

D Jiang, F Berger
  • Proceedings of the National Academy of Sciences , USA
  • 2017
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Chromatin assembly factor 1 ensures the stable maintenance of silent chromatin states in Arabidopsis.

Tatsuya Ono, Hidetaka Kaya, +7 authors Kei-ichi Shibahara
  • Genes to cells : devoted to molecular & cellular mechanisms
  • 2006
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

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