Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor

@inproceedings{Radtke2011TransgenerationalIO,
  title={Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor},
  author={Karl M. Radtke and M Ruf and Helen M Gunter and Katalin Dohrmann and M. Schauer and Andreas Meyer and Thomas Elbert},
  booktitle={Translational Psychiatry},
  year={2011}
}
Prenatal exposure to maternal stress can have lifelong implications for psychological function, such as behavioral problems and even the development of mental illness. Previous research suggests that this is due to transgenerational epigenetic programming of genes operating in the hypothalamic–pituitary–adrenal axis, such as the glucocorticoid receptor (GR). However, it is not known whether intrauterine exposure to maternal stress affects the epigenetic state of these genes beyond infancy. Here… CONTINUE READING
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