Transgenerational epigenetic inheritance in mammals: how good is the evidence?

@article{Otterdijk2016TransgenerationalEI,
  title={Transgenerational epigenetic inheritance in mammals: how good is the evidence?},
  author={Sanne D. Otterdijk and Karin B. Michels},
  journal={The FASEB Journal},
  year={2016},
  volume={30},
  pages={2457 - 2465}
}
Epigenetics plays an important role in orchestrating key biologic processes. Epigenetic marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are modified throughout life in response to environmental and behavioral influences. With each new generation, DNA methylation patterns are erased in gametes and reset after fertilization, probably to prevent these epigenetic marks from being transferred from parents to their offspring. However, some recent animal studies… 

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