Transgenerational Inheritance of Paternal Neurobehavioral Phenotypes: Stress, Addiction, Ageing and Metabolism

  title={Transgenerational Inheritance of Paternal Neurobehavioral Phenotypes: Stress, Addiction, Ageing and Metabolism},
  author={T. Yuan and Ang Li and X. Sun and Huan Ouyang and Carlos Campos and N. Rocha and {\'O}. Arias-Carri{\'o}n and Sergio Machado and Gonglin Hou and K. So},
  journal={Molecular Neurobiology},
  • T. Yuan, Ang Li, +7 authors K. So
  • Published 2015
  • Biology, Medicine
  • Molecular Neurobiology
  • Epigenetic modulation is found to get involved in multiple neurobehavioral processes. It is believed that different types of environmental stimuli could alter the epigenome of the whole brain or related neural circuits, subsequently contributing to the long-lasting neural plasticity of certain behavioral phenotypes. While the maternal influence on the health of offsprings has been long recognized, recent findings highlight an alternative way for neurobehavioral phenotypes to be passed on to the… CONTINUE READING
    25 Citations
    Multigenerational and transgenerational effects of paternal exposure to drugs of abuse on behavioral and neural function
    • 20
    Prenatal programming of stress responsiveness and behaviours: Progress and perspectives
    • 12
    Understanding the epigenetic basis of sex differences in depression
    • 34
    Transgenerational epigenetics: Integrating soma to germline communication with gametic inheritance
    • A. Sharma
    • Biology, Medicine
    • Mechanisms of Ageing and Development
    • 2017
    • 40
    Transgenerational transmission of maternal stimulatory experience in domesticated birds
    • L. Liu, N. Yang, +6 authors Y. Yu
    • Biology, Medicine
    • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
    • 2018
    • 4
    Obesity, male infertility, and the sperm epigenome.
    • 88
    Multi-, Inter-, and Transgenerational Effects of Drugs of Abuse on Behavior.
    • 2


    Lifetime stress experience: transgenerational epigenetics and germ cell programming
    • T. Bale
    • Biology, Medicine
    • Dialogues in clinical neuroscience
    • 2014
    • 73
    Epigenetic transgenerational inheritance of altered stress responses
    • 249
    • PDF
    Transgenerational Epigenetic Programming of the Brain Transcriptome and Anxiety Behavior
    • 247
    • PDF
    Epigenetic Transmission of the Impact of Early Stress Across Generations
    • 824
    • PDF
    Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals
    • 260
    • PDF
    Transgenerational neuroendocrine disruption of reproduction
    • 140
    Epigenetic mechanisms of depression and antidepressant action.
    • 198
    Epigenetic mechanisms of drug addiction
    • 112
    Environmental stress and epigenetic transgenerational inheritance
    • 91
    • PDF
    In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism
    • 387