Transgene silencing may be mediated by aberrant sense promoter sequence transcripts generated from cryptic promoters

Abstract

To investigate whether silencing of a T-DNA-carried nptII gene in five single-copy transgenic Arabidopsis lines might be due to position effects, genomic DNA flanking the insertions was analysed for gene density, GC content, presence of short repeats and transposable elements, i.e. factors suggested to promote silencing. No single, common factor could… (More)
DOI: 10.1007/s00018-005-5301-2

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