Transgelin as a suppressor is associated with poor prognosis in colorectal carcinoma patients

Abstract

We performed comparative proteomic analysis of colorectal cancer to investigate potential target proteins correlated with carcinogenesis and prognosis. Among them, transgelin, a 22 kDa protein also called SM22, was identified as a novel tumor suppressor protein, but little is known about this protein in tumors so far. A remarkable reduced expression of… (More)
DOI: 10.1038/modpathol.2009.144

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