Transfusion-related acute lung injury associated with interdonor incompatibility for the neutrophil-specific antigen HNA-1a.

@article{Lucas2000TransfusionrelatedAL,
  title={Transfusion-related acute lung injury associated with interdonor incompatibility for the neutrophil-specific antigen HNA-1a.},
  author={Geoffrey Lucas and Susan Rogers and Rachel E Evans and Henry Hambley and Nay Win},
  journal={Vox sanguinis},
  year={2000},
  volume={79 2},
  pages={112-5}
}
BACKGROUND AND OBJECTIVES A patient transfused with two pooled platelet concentrates became breathless. Bilateral infiltrates were seen on chest X-ray. A diagnosis of transfusion-related acute lung injury (TRALI) was made. The patient received 100% oxygen and recovered after 5 days. MATERIALS AND METHODS Antibody screening, cross-matching for granulocyte and lymphocyte antibodies and typing for granulocyte antigens was undertaken. RESULTS The patient typed as HNA-1b/HNA-1b. Granulocyte and… CONTINUE READING