Transfusion-related acute lung injury: report of a clinical look-back investigation.

  title={Transfusion-related acute lung injury: report of a clinical look-back investigation.},
  author={Patricia M. Kopko and Carol S. Marshall and Malcolm R. Mackenzie and Paul V. Holland and Mark A. Popovsky},
  volume={287 15},
CONTEXT Transfusion-related acute lung injury (TRALI) is a syndrome that includes dyspnea, hypotension, bilateral pulmonary edema, and fever. TRALI is the third leading cause of transfusion-related mortality, but it is probably underdiagnosed and underreported. OBJECTIVE To determine if blood products from a frequent plasma donor, whose blood product was implicated in a fatal case of TRALI, caused symptoms of TRALI in other recipients of her plasma. DESIGN, SETTING, AND PARTICIPANTS… CONTINUE READING

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