Transfusion of stored red blood cells adhere in the rat microvasculature.

@article{ChinYee2009TransfusionOS,
  title={Transfusion of stored red blood cells adhere in the rat microvasculature.},
  author={Ian H. Chin-Yee and Leslie A Gray-Statchuk and Stephanie Milkovich and Christopher Gerald Ellis},
  journal={Transfusion},
  year={2009},
  volume={49 11},
  pages={2304-10}
}
BACKGROUND Ex vivo storage of red blood cells (RBCS) for transfusions is associated with a "storage lesion," which decreases RBC deformability and increases RBC adhesiveness to vascular endothelium. This may impair microcirculatory flow with deleterious effects on oxygen delivery after transfusion. Previous studies have shown that human RBCs adhere to… CONTINUE READING