Transfusion of prion-filtered red cells does not increase the rate of alloimmunization or transfusion reactions in patients: results of the UK trial of prion-filtered versus standard red cells in surgical patients (PRISM A).

@article{Elebute2013TransfusionOP,
  title={Transfusion of prion-filtered red cells does not increase the rate of alloimmunization or transfusion reactions in patients: results of the UK trial of prion-filtered versus standard red cells in surgical patients (PRISM A).},
  author={Modupe O Elebute and Louise Choo and Ana Lorena Mora and Coral MacRury and Charlotte A Llewelyn and Shilpi Purohit and Vicky Hicks and Caroline Casey and Moira Malfroy and Alison Deary and T. Edward Reed and Sarah Meredith and Lynn M. Manson and Lorna M. Williamson},
  journal={British journal of haematology},
  year={2013},
  volume={160 5},
  pages={701-8}
}
This study, conducted for the UK Blood Transfusion Services (UKBTS), evaluated the clinical safety of red cells filtered through a CE-marked prion removal filter (P-Capt™). Patients requiring blood transfusion for elective procedures in nine UK hospitals were entered into a non-randomized open trial to assess development of red cell antibodies to standard… CONTINUE READING