Transfusion criteria for fresh frozen plasma in liver resection: a 3 + 3 cohort expansion study.

Abstract

OBJECTIVE To establish transfusion criteria for use of fresh frozen plasma (FFP) in liver resection. BACKGROUND Fresh frozen plasma has been transfused in liver resection without adequate supporting evidence, leading to unnecessary use. DESIGN Prospective study using a phase 1 dose-escalation, 3 + 3 cohort expansion design, modified for FFP transfusion… (More)
DOI: 10.1001/archsurg.2011.293

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