Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme.

Abstract

Transforming growth factor beta (TGFbeta) signaling has an increasing interest in regenerative medicine as a potential tool to repair cartilages, however the chondrogenic effect of this pathway in developing systems is controversial. Here we have analyzed the function of TGFbeta signaling in the differentiation of the developing limb mesoderm in vivo and in… (More)
DOI: 10.1074/jbc.M109.014811

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