Transforming growth factor-beta1-induced CD4+CD25+ regulatory T cells in vitro reverse and prevent a murine lupus-like syndrome of chronic graft-versus-host disease.

Abstract

BACKGROUND The suppressive mechanism of CD4+CD25+ regulatory T cells (Tregs) is poorly understood. It is also not known how to obtain enough peripheral Tregs, and how to make them effective in ameliorating a murine lupus-like syndrome of chronic graft-versus-host disease (cGVHD). OBJECTIVES To confirm the contribution of transforming growth factor (TGF… (More)
DOI: 10.1111/j.1365-2133.2008.08555.x

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@article{Su2008TransformingGF, title={Transforming growth factor-beta1-induced CD4+CD25+ regulatory T cells in vitro reverse and prevent a murine lupus-like syndrome of chronic graft-versus-host disease.}, author={H. Su and Dong Ye and B-L Wang and X-H Fang and J. Chen and Q. Wang and W-X Li and N. Zhang}, journal={The British journal of dermatology}, year={2008}, volume={158 6}, pages={1197-209} }