Transforming growth factor-beta distribution in basal cell carcinomas: relationship to proliferation index.

@article{Stamp1993TransformingGF,
  title={Transforming growth factor-beta distribution in basal cell carcinomas: relationship to proliferation index.},
  author={Gordon Stamp and Mahwish Nasim and Maria Rosaria Cardillo and S G Sudhindra and E. N. Lalani and Massimo N. Pignatelli},
  journal={The British journal of dermatology},
  year={1993},
  volume={129 1},
  pages={57-64}
}
Transforming growth factor-beta (TGF-beta) distribution in basal cell carcinomas (BCCs) was studied using polyclonal antibodies recognizing intra- (precursor) and extracellular (activated) forms (LC 1-30 and CC 1-30), and compared with an index of cell proliferation (PCNA immunoreactivity). Intracellular TGF-beta is found in suprabasal keratinocytes and the outer root sheath. Extracellular TGF-beta is largely absent from normal skin, but is abundant in the intracellular spaces of hyperplastic… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…