Transforming growth factor-beta and bcl-2 distribution patterns distinguish trichoepithelioma from basal cell carcinoma.

@article{Verhaegh1997TransformingGF,
  title={Transforming growth factor-beta and bcl-2 distribution patterns distinguish trichoepithelioma from basal cell carcinoma.},
  author={M E J M Verhaegh and Jan Willem Arends and I M Leonie Majoie and Rick Hoekzema and H A Martino Neumann},
  journal={Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]},
  year={1997},
  volume={23 8},
  pages={695-700}
}
BACKGROUND Trichoepithelioma (TE) and basal cell carcinoma (BCC) have many features in common both clinically and histologically. Despite these many similarities TE and BCC represent different biological entities. OBJECTIVE Recently, bcl-2 and CD34 have been reported as reliable markers in distinguishing the two types of tumor. Transforming growth factor-beta (TGF-beta), a multifunctional regulator of both cell growth and differentiation, was evaluated in this study. METHODS The… CONTINUE READING

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