Transforming growth factor beta 1 is an epithelial-derived signal peptide that influences otic capsule formation.

@article{Frenz1992TransformingGF,
  title={Transforming growth factor beta 1 is an epithelial-derived signal peptide that influences otic capsule formation.},
  author={Dorothy A. Frenz and Vera Galinovic-Schwartz and Wenguang Liu and Kathleen Corey Flanders and Thomas R Van De Water},
  journal={Developmental biology},
  year={1992},
  volume={153 2},
  pages={
          324-36
        }
}
Interactions between epithelial and mesenchymal tissues in the developing inner ear direct the formation of its cartilaginous capsule. Recent work indicates that many growth factors are distributed in the early embryo in vivo in a temporal-spatial pattern that correlates with sites of ongoing morphogenetic events. We report here that the localization of transforming growth factor beta 1 (TGF-beta 1) in both epithelial and mesenchymal tissues of the mouse inner ear between 10 and 16 days of… CONTINUE READING
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