Transforming growth factor-beta 1 post-transcriptionally inhibits mouse growth hormone releasing factor secretion in placenta.

@article{Yamaguchi1994TransformingGF,
  title={Transforming growth factor-beta 1 post-transcriptionally inhibits mouse growth hormone releasing factor secretion in placenta.},
  author={Maki Yamaguchi and Hitoshi Endo and Tadao Maeda and Minoru Tahara and Mafasumi Ono and Naomasa Miki and Akira Miyake},
  journal={Biochemical and biophysical research communications},
  year={1994},
  volume={204 3},
  pages={1206-11}
}
The aim of this study was to investigate whether TGF-beta 1 regulates mouse GHRF secretion by primary cultures of placental cells from day 12 of pregnancy. Ten ng/ml TGF-beta 1 significantly inhibited mouse GHRF secretion by the third day of culture. The lowest concentration of TGF-beta 1 that significantly inhibited mouse GHRF secretion was 1 ng/ml. The… CONTINUE READING