Transforming growth factor-beta (TGF-beta) and tissue transglutaminase expression in the small intestine in children with coeliac disease.

@article{Hansson2002TransformingGF,
  title={Transforming growth factor-beta (TGF-beta) and tissue transglutaminase expression in the small intestine in children with coeliac disease.},
  author={T. H. Hansson and A K Ulfgren and Eva Lindroos and Anders Dannaeus and Ingrid Dahlbom and Lars Klareskog},
  journal={Scandinavian journal of immunology},
  year={2002},
  volume={56 5},
  pages={530-7}
}
The production of cytokines from T cells and macrophages is of potential importance for the histological changes apparent in coeliac disease (CoD). Small intestinal biopsy specimens from children with CoD and disease control subjects were investigated for their content of cytokines and tissue transglutaminase (tTG). The transforming growth factor-beta1 (TGF-beta1) expression was increased in the lamina propria of children with villous atrophy. In contrast, TGF-beta3 was expressed at a higher… CONTINUE READING

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