Transforming growth factor alpha.

  title={Transforming growth factor alpha.},
  author={V. Barath Kumar and Stephen Bustin and Iain McKay},
  journal={Cell biology international},
  volume={19 5},
Transforming growth factor alpha (TGF alpha) is a close relative of epidermal growth factor (EGF), the first polypeptide mitogen discovered in 1962 (Cohen, 1962). TGF alpha, like EGF, exerts its effect on cells through binding to the EGF-Receptor (EGF-R). Here we review the molecular and cell biology of TGF alpha before proceeding to describe our own work… CONTINUE READING