Transforming growth factor-alpha stimulates proliferation of mammotrophs and corticotrophs in the mouse pituitary.

@article{Oomizu2000TransformingGF,
  title={Transforming growth factor-alpha stimulates proliferation of mammotrophs and corticotrophs in the mouse pituitary.},
  author={Souichi Oomizu and Junichi Honda and Sakae Takeuchi and Tomoshi Kakeya and Tohru Masui and Sumio Takahashi},
  journal={The Journal of endocrinology},
  year={2000},
  volume={165 2},
  pages={493-501}
}
Oestrogen stimulates the proliferation of pituitary cells. The present study was designed to clarify the involvement of transforming growth factor-alpha (TGF-alpha) in the oestrogen-induced growth of mouse pituitary cells in vitro. Anterior pituitary cells obtained from ICR male mice were cultured in a primary serum-free culture system. Proliferation of pituitary cells was detected by monitoring the cellular uptake of bromodeoxyuridine. Secretory cell types were immunocytochemically determined… CONTINUE READING

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Since TGF - alpha binds to the epidermal growth factor ( EGF ) receptor , this action may be exerted through the EGF receptor . Oestradiol-17beta
Transforming Growth FactorsIs biochemical function of gene productTGFA protein, human
The present study was designed to clarify the involvement of transforming growth factor - alpha ( TGF - alpha ) in the oestrogen - induced growth of mouse pituitary cells in vitro .
Since TGF - alpha binds to the epidermal growth factor ( EGF ) receptor , this action may be exerted through the EGF receptor . Oestradiol-17beta
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