Transforming growth factor Beta-releasing scaffolds for cartilage tissue engineering.

  title={Transforming growth factor Beta-releasing scaffolds for cartilage tissue engineering.},
  author={Henning Madry and Ana Rey-Rico and Jagadeesh Kumar Venkatesan and Brian Johnstone and Magali Cucchiarini},
  journal={Tissue engineering. Part B, Reviews},
  volume={20 2},
The maintenance of a critical threshold concentration of transforming growth factor beta (TGF-β) for a given period of time is crucial for the onset and maintenance of chondrogenesis. Thus, the development of scaffolds that provide temporal and/or spatial control of TGF-β bioavailability has appeal as a mechanism to induce the chondrogenesis of stem cells in vitro and in vivo for articular cartilage repair. In the past decade, many types of scaffolds have been designed to advance this goal… CONTINUE READING
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