Transforming growth factor(beta)-mediated corneal myofibroblast differentiation requires actin and fibronectin assembly.

@article{Jester1999TransformingGF,
  title={Transforming growth factor(beta)-mediated corneal myofibroblast differentiation requires actin and fibronectin assembly.},
  author={James V. Jester and Jiying Huang and Patricia Barry-Lane and Winston W. Y. Kao and Walter Matthew Petroll and Harrison Dwight Cavanagh},
  journal={Investigative ophthalmology & visual science},
  year={1999},
  volume={40 9},
  pages={1959-67}
}
PURPOSE Recent studies indicate that transforming growth factor (TGF)beta is a potent inducer of corneal myofibroblast differentiation and expression of smooth muscle-specific, alpha-actin (alpha-SMA). Although TGFbeta is known to enhance synthesis of extracellular matrix proteins and receptors, little is known about how it modulates the expression of… CONTINUE READING