Transforming genes from familial adenomatous polyposis patient cells detected by a tumorigenicity assay.

Abstract

We tried to detect oncogenes associated with familial adenomatous polyposis by a tumorigenicity assay in nude mice. One polyp and two peripheral blood lymphocyte DNAs out of 12 samples from patients induced Alu-positive tumors. Lymphocyte DNAs from one of 5 healthy people also showed tumorigenic activity. The transforming genes of polyps from a patient and… (More)

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Cite this paper

@article{Yuasa1990TransformingGF, title={Transforming genes from familial adenomatous polyposis patient cells detected by a tumorigenicity assay.}, author={Yasuhito Yuasa and Toshiya Kamiyama and Masahiko Kato and Toru Iwama and T Ikeuchi and Akira Tonomura}, journal={Oncogene}, year={1990}, volume={5 4}, pages={589-96} }