Transformed cells exhibit altered response to db cycle amp-mediated modulation of protein phosphorylation and different endogenous phosphoprotein acceptors.

Abstract

Endogenous protein phosphorylation has been studied in extracts from rat cells transformed by temperature-sensitive derivatives of Rous sarcoma virus which can reversibly express a transformed behavior at 33 degrees C and reacquire "normal" properties at 39 degrees C. The expression of transformation appeared associated with marked alterations in the type… (More)

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