Transformations in null mutants of Hox genes: do they represent intercalary regenerates?

@article{Crawford1995TransformationsIN,
  title={Transformations in null mutants of Hox genes: do they represent intercalary regenerates?},
  author={Meghan Crawford},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={1995},
  volume={17 12},
  pages={
          1065-73
        }
}
In the minds of many, Hox gene null mutant phenotypes have confirmed the direct role that these genes play in specifying the pattern of vertebrate embryos. The genes are envisaged as defining discrete spatial domains and, subsequently, conferring specific segmental identities on cells undergoing differentiation along the antero-posterior axis. However, several aspects of the observed mutant phenotypes are inconsistent with this view. These include: the appearance of other, unexpected… CONTINUE READING

References

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