Transformation of the antiepileptic drug oxcarbazepine upon different water disinfection processes.

@article{Li2011TransformationOT,
  title={Transformation of the antiepileptic drug oxcarbazepine upon different water disinfection processes.},
  author={Zhi Li and H{\'e}l{\`e}ne Fenet and Elena G{\'o}mez and Serge Chir{\'o}n},
  journal={Water research},
  year={2011},
  volume={45 4},
  pages={
          1587-96
        }
}
Transformation of the pharmaceutical oxcarbazepine (OXC), a keto analogue of carbamazepine (CBZ) was investigated under different water disinfection processes (ozonation, chlorination and UV irradiation) to compare its persistence, toxicity and degradation pathways with those of CBZ. Analysis by LC-ion trap-MS(n) allowed for the identification of up to thirteen transformation products (TPs). The major abundant and persistent TPs (10,11-dihydro-10,11-trans-dihydroxy-carbamazepine (DiOH-CBZ… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

Degradation of oxcarbazepine by UV-activated persulfate oxidation: kinetics, mechanisms, and pathways

  • Environmental Science and Pollution Research
  • 2015
VIEW 9 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Monitoring of methotrexate chlorination in water.

  • Water research
  • 2014
VIEW 1 EXCERPT
CITES BACKGROUND