Transformation of hemopoietic stem cells by phytohemagglutinin (PHA) II. Mechanism of action.

Abstract

It has long been known that phytohemagglutinin (PHA) stimulates transformation and growth of immune competent lymphocytes. Lymphoid cell colonies have previously been shown in the spleen with PHA treated lymph node cells from donor mice were injected into irradiated mice. This communication reports the results of in vivo effects of PHA stimulation on agar… (More)

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