Transformation of ferulic acid to vanillin using a fed-batch solid-liquid two-phase partitioning bioreactor.

@article{Ma2014TransformationOF,
  title={Transformation of ferulic acid to vanillin using a fed-batch solid-liquid two-phase partitioning bioreactor.},
  author={Xiao-kui Ma and Andrew J. Daugulis},
  journal={Biotechnology progress},
  year={2014},
  volume={30 1},
  pages={207-14}
}
Amycolatopsis sp. ATCC 39116 (formerly Streptomyces setonii) has shown promising results in converting ferulic acid (trans-4-hydroxy-3-methoxycinnamic acid; substrate), which can be derived from natural plant wastes, to vanillin (4-hydroxy-3-methoxybenzaldehyde). After exploring the influence of adding vanillin at different times during the growth cycle on cell growth and transformation performance of this strain and demonstrating the inhibitory effect of vanillin, a solid-liquid two-phase… CONTINUE READING

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