Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine.

@article{Sun2016TransformableDN,
  title={Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine.},
  author={Wujin Sun and Wenyan Ji and Quanyin Hu and Jicheng Yu and Chao Wang and Chenggen Qian and Gabrielle M Hochu and Zhen Gu},
  journal={Biomaterials},
  year={2016},
  volume={96},
  pages={1-10}
}
Direct delivery of cytokines using nanocarriers holds great promise for cancer therapy. However, the nanometric scale of the vehicles made them susceptible to size-dependent endocytosis, reducing the plasma membrane-associated apoptosis signaling. Herein, we report a tumor microenvironment-responsive and transformable nanocarrier for cell membrane targeted… CONTINUE READING