Transferrin receptors-targeting nanocarriers for efficient targeted delivery and transcytosis of drugs into the brain tumors: a review of recent advancements and emerging trends

@article{Choudhury2018TransferrinRN,
  title={Transferrin receptors-targeting nanocarriers for efficient targeted delivery and transcytosis of drugs into the brain tumors: a review of recent advancements and emerging trends},
  author={H. Choudhury and Manisha Pandey and Pei Xin Chin and Y. Phang and J. Y. Cheah and Shu Chien Ooi and Kit-Kay Mak and M. R. Pichika and P. Kesharwani and Zahid Hussain and Bapi Gorain},
  journal={Drug Delivery and Translational Research},
  year={2018},
  volume={8},
  pages={1545-1563}
}
  • H. Choudhury, Manisha Pandey, +8 authors Bapi Gorain
  • Published 2018
  • Medicine
  • Drug Delivery and Translational Research
  • Treatment of glioblastoma multiforme (GBM) is a predominant challenge in chemotherapy due to the existence of blood–brain barrier (BBB) which restricts delivery of chemotherapeutic agents to the brain together with the problem of drug penetration through hard parenchyma of the GBM. With the structural and mechanistic elucidation of the BBB under both physiological and pathological conditions, it is now viable to target central nervous system (CNS) disorders utilizing the presence of transferrin… CONTINUE READING
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