Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis.

@article{Forejtnkov2010TransferrinR2,
  title={Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis.},
  author={Hana Forejtn{\'i}kov{\'a} and Maud Vieillevoye and Yael Zermati and Mireille Lambert and Rosa Maria Pellegrino and Soizic Guihard and Muriel Gaudry and Clara Camaschella and Catherine Lacombe and A Roetto and Patrick Mayeux and Fr{\'e}d{\'e}rique Verdier},
  journal={Blood},
  year={2010},
  volume={116 24},
  pages={5357-67}
}
Erythropoietin (Epo) is required for erythroid progenitor differentiation. Although Epo crosslinking experiments have revealed the presence of Epo receptor (EpoR)-associated proteins that could never be identified, EpoR is considered to be a paradigm for homodimeric cytokine receptors. We purified EpoR-binding partners and identified the type 2 transferrin receptor (TfR2) as a component of the EpoR complex corresponding to proteins previously detected in cross-linking experiments. TfR2 is… CONTINUE READING

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References

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Comparison of three Tfr2-deficient murine models suggests distinct functions for TFR2 alpha and beta isoforms in different tissues

  • A Roetto, F Di Cunto, RM Pellegrino
  • 2010

parison of three Tfr 2deficient murine models suggests distinct functions for TFR 2 alpha and beta isoforms in different tissues

  • A Roetto, F DiCunto, RM Pellegrino
  • Blood
  • 2010

Natural history of TFR2-related hereditary hemochromatosis in a 47-yr-old Italian patient

  • BM Ricerca, FC Radio, L De Marinis
  • Eur J Haematol
  • 2009

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