Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics.

@article{Sonali2016TransferrinLO,
  title={Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics.},
  author={Sonali and R P Singh and Nitesh Singh and Gunjan Sharma and Mahalingam Rajamanickam Vijayakumar and Biplob Koch and Sanjay Kumar Singh and Usha Singh and Debabrata Dash and Bajarangprasad L Pandey and Madaswamy Sona Muthu},
  journal={Drug delivery},
  year={2016},
  volume={23 4},
  pages={1261-71}
}
Diagnosis and therapy of brain cancer was often limited due to low permeability of delivery materials across the blood-brain barrier (BBB) and their poor penetration into the brain tissue. This study explored the possibility of utilizing theranostic d-alpha-tocopheryl polyethylene glycol 1000 succinate mono-ester (TPGS) liposomes as nanocarriers for minimally invasive brain-targeted imaging and therapy (brain theranostics). The aim of this work was to formulate transferrin conjugated TPGS… CONTINUE READING
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