Transferrin induces interleukin-18 expression in chronic myeloid leukemia cell line, K-562.

Abstract

Transferrin is an iron carrier protein involved in iron uptake and the regulation of cell growth. Although highly proliferative cells express transferrin and its receptor, little is known about the role of transferrin in the cellular response to cytokine production. The non-iron-bound form of transferrin (apo-transferrin) was administered to human chronic… (More)
DOI: 10.1016/j.leukres.2008.08.001

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