Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis

@article{Veras1992TransferOZ,
  title={Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis},
  author={Peixoto Veras and Chantal de Chastellier and Marlene Rabinovitch},
  journal={The Journal of Experimental Medicine},
  year={1992},
  volume={176},
  pages={639 - 646}
}
Leishmania are flagellated protozoan parasites which, in their amastigote stages, survive and multiply within phagolysosome-like parasitophorous vacuoles (PV) of mammalian macrophages (MO). This study develops an earlier ultrastructural, incidental observation that zymosan particles (Z) were transferred to the PV of macrophages infected with Leishmania amazonensis. In the present report, a pulse-chase light microscopic assay was used to delineate several features of the Z transfer. The assay… CONTINUE READING

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