Transfer of the human NaI symporter gene enhances iodide uptake in hepatoma cells.

Abstract

UNLABELLED The characteristic feature of thyroid cells of taking up iodide enables benign thyroid diseases and differentiated thyroid carcinoma to be successfully treated with radioiodide therapy. The transport of iodide across the cell membrane is mediated by the human NaI symporter (hNIS). We therefore investigated whether the accumulation of iodide may… (More)

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