Transfer of paternal mitochondrial DNA during fertilization of honeybee (Apis mellifera L.) eggs

  title={Transfer of paternal mitochondrial DNA during fertilization of honeybee (Apis mellifera L.) eggs},
  author={Michael S. Meusel and Robin F. A. Moritz},
  journal={Current Genetics},
Strict maternal inheritance of mitochondrial (mt) DNA is believed to be the rule in most eukaryotic organisms because of exclusion of paternal mitochondria from the egg cytoplasm during fertilization. In honeybees, polyspermic fertilization occurs, and many spermatozoa, including their mitochondria-rich flagellum, can completely penetrate the egg, thus allowing for a possibly high paternal leakage. In order to identify paternal mtDNA in honeybee eggs, restriction fragment length polymorphisms… 

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It is indicated that under appropriate conditions, paternal leakage occurs in the mtDNA of parasitic nematodes, and the hypothesis that hybrid zones facilitate paternal leakage is supported.

Evidence for Paternal Leakage in Hybrid Periodical Cicadas (Hemiptera: Magicicada spp.)

Evidence of paternal leakage in both reciprocal hybrid crosses and relative difficulty of detecting paternal mtDNA in the youngest eggs and ease of detecting leakage in older eggs and in nymphs suggests that paternal mitochondria proliferate as the eggs develop.

Paternal comeback in mitochondrial DNA inheritance

  • J. Vissing
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    Proceedings of the National Academy of Sciences
  • 2019
This report in PNAS reports on biparental inheritance in three families, which challenges the notion of strict maternal transmission of mtDNA to offspring.

Analysis of nuclear copies of mitochondrial sequences in honeybee (Apis mellifera) genome.

  • S. Behura
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  • 2007
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Recombination in Mitochondrial DNA of European Mussels Mytilus

Re rearranged mtDNA genomes found in all three European Mytilus species are described and some of the mosaic genomes do not show any gender bias, which has important implications regarding the transmission and evolution of blue mussel mitochondrial genomes.

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Detection of recombinant mitochondrial genomes: Implications for the mechanism of mtDNA inheritance in mussel Mytilus

Mussels of the genus Mytilus possess two types of mitochondrial genomes inherited from males and females, respectively, and their mode of mtDNA inheritance is called doubly uniparental inheritance (DUI), and the presence of two highly diverged parental molecules gives the opportunity for detection of recombinant variants.



Incomplete maternal transmission of mitochondrial DNA in Drosophila.

The possibility of incomplete maternal transmission of mitochondrial DNA (mtDNA) in Drosophila, previously suggested by the presence of heteroplasmy, was examined by intra- and interspecific backcrosses of Dosophila simulans and its closest relative, Drosophile mauritiana, and showed clear evidence for paternal leakage of mtDNA.

Direct evidence for extensive paternal mitochondrial DNA inheritance in the marine mussel Mytilus

Results from pair-matings involving two species of mussels show extensive contribution of paternal mtDNA, amounting to several orders of magnitude higher than that inferred for Drosophila or mice, was observed in both intra-and interspecific crosses.

Maternal and cytoplasmic inheritance of mitochondrial DNA in Xenopus.

Critical experimental test of the possibility of "paternal leakage" of mitochondrial DNA.

Analyzing the 45- and 91-generation backcross progeny of such matings between two species of lepidopteran insects using autoradiographic techniques failed to detect any paternal mtDNA and sets an upper limit of paternal leakage at about 1 molecule per 25,000 per generation in this system.

Chloroplast and mitochondrial DNA are paternally inherited in Sequoia sempervirens D. Don Endl.

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Evidence from mitochondrial DNA that African honey bees spread as continuous maternal lineages

The migrating force of the African honey bee in the American tropics consists of continuous African maternal lineages spreading as swarms, and the mating of African drones to European queens seems to contribute little to African bee migration.

A mitochondrial DNA polymorphism in honeybees (Apis mellifera L.)

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Maternal inheritance of mitochondrial DNA during backcrossing of two species of mice.

As judged by restriction analysis, mitochondrial DNA shows strictly maternal inheritance during 6-8 generations of backcrossing in both directions between Mus domesticus and Mus spretus. The average