Transfer of maternal cholesterol to embryo and fetus in pregnant mice.

  title={Transfer of maternal cholesterol to embryo and fetus in pregnant mice.},
  author={Shumi Yoshida and Yoshinao Wada},
  journal={Journal of lipid research},
  volume={46 10},
Cholesterol is essential for antenatal development. However, the transport of maternal cholesterol to the embryo has not been sufficiently studied, and that to the fetus is still controversial. To this end, a 1 mg dose of [3,4-(13)C(2)]cholesterol was injected daily into pregnant mice and the labeled cholesterol was measured by gas chromatography-mass spectrometry. After venous injections from days 10 to 17 of gestation, [(13)C]cholesterol levels in total ((12)C and (13)C) cholesterol were… CONTINUE READING


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