Transfer of antitumor immunity with ribonucleic acid-containing spleen extract of immunized animals

Ribonucleic acid-containing spleen extract (i-extract) was prepared from the spleens of C57BL/6 mice immunized with mammary carcinoma Ca755. The i-extract contained a factor which could transfer antitumor immunity into the recipient mice, since the tumor growth was significantly retarded if mice received IP injections of i-extract at the same time as or at… CONTINUE READING