Transfer of Intracellular HIV Nef to Endothelium Causes Endothelial Dysfunction

@inproceedings{Wang2014TransferOI,
  title={Transfer of Intracellular HIV Nef to Endothelium Causes Endothelial Dysfunction},
  author={Ting Wang and Linden Ann Green and Samir K Gupta and Chul T Kim and Liang Wang and Sharilyn Almod{\'o}var and S Cisneros Flores and Igor A. Prudovsky and Paul Jolicoeur and Ziyue Liu and Matthias A. Clauss},
  booktitle={PloS one},
  year={2014}
}
With effective antiretroviral therapy (ART), cardiovascular diseases (CVD) are emerging as a major cause of morbidity and death in the aging HIV-infected population. To address whether HIV-Nef, a viral protein produced in infected cells even when virus production is halted by ART, can lead to endothelial activation and dysfunction, we tested Nef protein… CONTINUE READING