Transfer of HLA-Specific Allosensitization From a Highly Sensitized Deceased Organ Donor to the Recipients of Each Kidney

@article{Maxfield2015TransferOH,
  title={Transfer of HLA-Specific Allosensitization From a Highly Sensitized Deceased Organ Donor to the Recipients of Each Kidney},
  author={Steve Maxfield and Craig J. Taylor and Vasilios Kosmoliaptsis and Verena Broecker and Christopher J E Watson and J Andrew Bradley and Sarah Peacock},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2015},
  volume={15 9},
  pages={2501-6}
}
We report for the first time the adoptive transfer of donor HLA-specific allosensitization in two recipients following kidney transplantation from a highly sensitized donor. Kidneys from a donation after circulatory death donor were transplanted into two nontransfused, HLA-specific antibody negative males receiving their first transplant. Antibody screening 7 days after transplant showed high level de novo IgG HLA class I- and class II-specific antibodies in both recipients, with largely… CONTINUE READING
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