Transfer of Cl- across placenta of anesthetized rat.

  title={Transfer of Cl- across placenta of anesthetized rat.},
  author={Jaroslav Stulc and B. {\vS}tulcov{\'a} and Saba Husain and Colin P Sibley},
  journal={The American journal of physiology},
  volume={271 5 Pt 2},
The mechanisms of Cl- transfer across the rat placenta have been investigated. Clearance across the intact placenta from mother to fetus (m-->f) of 51Cr-EDTA (paracellular diffusion marker) and 36Cl- (Kmf) was 1.9 +/- 0.1 and 37.3 +/- 4.1 microliters/min, respectively (mean +/- SE, n = 10), the large difference indicating that most m-->f transfer of Cl- is transcellular. The clearance of 36Cl- across the dually perfused placenta in m-->f and fetal-to-maternal directions was symmetrical and… CONTINUE READING