Transfer conditions and transmission bias in capillaries of vacuum interfaces
@article{Bernier2019TransferCA, title={Transfer conditions and transmission bias in capillaries of vacuum interfaces}, author={Laurent Bernier and M. Taesch and Stephan Rauschenbach and Julius Reiss}, journal={International Journal of Mass Spectrometry}, year={2019} }
Figures and Tables from this paper
6 Citations
Charging Effects in Inlet Capillaries.
- PhysicsJournal of the American Society for Mass Spectrometry
- 2022
Glass or metal inlet capillaries are commonly used for flow restriction in atmospheric pressure ionization mass spectrometers. They exhibit a high ion transmission rate and stability at most…
Numerical Simulation of Flow Field and Ion Transport for Different Ion Source Sampling Interfaces of a Mass Spectrometer.
- PhysicsJournal of the American Society for Mass Spectrometry
- 2020
Numerical simulations of three types of ions in two different MS interface designs have been carried out, showing that a flat plate interface has a higher peak buffer gas velocity but a narrower zone of silence compared to the conical interface.
Ion Formation from Rapidly Heated Aqueous Droplets by Droplet Assisted Ionization.
- PhysicsThe journal of physical chemistry. A
- 2020
The conditions allowing initial droplets to break up into progeny droplets were studied by computational fluid dynamics (CFD) with a droplet evaporation model, and the results were used to interpret experimental measurements of ion current vs. capillary wall temperature.
Multiplexing of Electrospray Ionization Sources Using Orthogonal Injection into an Electrodynamic Ion Funnel.
- PhysicsAnalytical chemistry
- 2021
An efficient approach to multiplex electrospray ionization (ESI) sources for applications in analytical and preparative mass spectrometry and a pronounced effect of gas dynamics on the ion trajectories in the ion funnel, indicating that the efficiency of multiplexing strongly depends on gas velocity field.
A Preparative Mass Spectrometer to Deposit Intact Large Native Protein Complexes
- BiologyACS nano
- 2022
A module that adds ion-beam deposition capabilities to a popular commercial MS platform (Thermo Scientific Q Exactive UHMR mass spectrometer) significantly reduces the overhead associated with custom instruments, while benefiting from established high performance and reliability.
Navigate Flying Molecular Elephants Safely to the Ground: Mass-Selective Soft Landing up to the Mega-Dalton Range by Electrospray Controlled Ion-Beam Deposition
- PhysicsAnalytical chemistry
- 2022
The prototype of a highly versatile and efficient preparative mass spectrometry system used for the deposition of molecules in ultrahigh vacuum (UHV) is presented, along with encouraging performance…
26 References
Gas Flow and Ion Transfer in Heated ESI Capillary Interfaces
- PhysicsJournal of The American Society for Mass Spectrometry
- 2018
This work investigates the ion transport through capillaries by numerical simulation of interacting ions through a one-dimensional gas dynamics description, and investigates the influence of the capillary heating on the gas flow and by this on the ions transport.
Ion transport by viscous gas flow through capillaries
- PhysicsJournal of the American Society for Mass Spectrometry
- 1994
A hydrodynamically optimized nano-electrospray ionization source and vacuum interface.
- PhysicsThe Analyst
- 2014
This work presents a nano-ESI vacuum interface optimized to exploit the hydrodynamic drag of the background gas for collimation and the reduction of space charge repulsion and shows how the specific shape enhances the collimation of the ion cloud.
Numerical Modeling of Ion Transport in an ESI-MS System
- PhysicsJournal of The American Society for Mass Spectrometry
- 2014
Numerical results indicate that as many as 75% of the ions that exit from the capillary are lost on the conical surface of the skimmer or capillary outer surface because of the electrostatic force and plume divergence.
Numerical simulation of ion transport in an atmosphere-to-vacuum interface taking into account gas dynamics and space charge
- PhysicsEuropean journal of mass spectrometry
- 2017
A two-step approach was developed for the study of ion transport in an atmospheric pressure interface and the simulations show that the influence of the space charge is the main contributor to the loss of ion current in the heated capillary.
Gas Flow in the Capillary of the Atmosphere-to-Vacuum Interface of Mass Spectrometers
- Physics, EngineeringJournal of The American Society for Mass Spectrometry
- 2017
A conclusion was drawn that the detailed digital laminar model is able to quantitatively describe the measured gas flow rates through the capillaries under conditions considered.
Simulation of Ion Motion at Atmospheric Pressure: Particle Tracing Versus Electrokinetic Flow
- PhysicsJournal of The American Society for Mass Spectrometry
- 2011
Results obtained with two computational approaches for the simulation of ion motion at elevated pressure are compared with experimentally derived ion current data and show very good agreement between the SIMION/SDS model and experimental data.
Design and performance of a high-flux electrospray ionization source for ion soft landing.
- PhysicsThe Analyst
- 2015
A new high-intensity electrospray ionization source for ion soft-landing experiments that incorporates a dual ion funnel, which enables operation with a higher gas load through an expanded diameter heated inlet into the additional first region of differential pumping is reported.
Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface
- PhysicsJournal of the American Society for Mass Spectrometry
- 2007
Gas Flow Dynamics in Inlet Capillaries: Evidence for non Laminar Conditions
- Physics, EngineeringJournal of The American Society for Mass Spectrometry
- 2016
It is suggested that laminar conditions inside inlet capillaries are not a valid primary explanation for the observed high ion transparency of inletcapillaries under common operation conditions.