Transfer and expression of the interferon gamma gene in human endothelial cells inhibits vascular smooth muscle cell growth in vitro.

Abstract

Intimal hyperplasia in blood vessels is primarily caused by the migration and proliferation of vascular smooth muscle cells. Excessive intimal thickening characterizes atherosclerosis as well as bypass graft and angioplasty failures. Endothelial cell-smooth muscle cell interactions and local cytokine production are important regulators of smooth muscle cell… (More)

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@article{Stopeck1997TransferAE, title={Transfer and expression of the interferon gamma gene in human endothelial cells inhibits vascular smooth muscle cell growth in vitro.}, author={Alison T Stopeck and Mostafa Vahedian and S. K. Williams}, journal={Cell transplantation}, year={1997}, volume={6 1}, pages={1-8} }