Transfer RNA genes frequently serve as integration sites for prokaryotic genetic elements.

@article{Reiter1989TransferRG,
  title={Transfer RNA genes frequently serve as integration sites for prokaryotic genetic elements.},
  author={W. D. Reiter and P. Palm and Siobhan M. Yeats},
  journal={Nucleic acids research},
  year={1989},
  volume={17 5},
  pages={1907-14}
}
The DNA sequences were determined at the boundaries of the integrated copy of the archaebacterial genetic element SSV1. A 44 bp sequence present as a single copy on the 15.5 kb circular SSV1 DNA flanked the integrated copy as a direct DNA sequence repeat, suggesting that SSV1 integration occurred by recombination between this 44 bp SSV1 sequence and an identical sequence on the bacterial chromosome. At the left attachment site, a region encompassing the 44 bp attachment core sequence and the 31… CONTINUE READING