Transfection of a DNA locus that mediates the conversion of 10T1 2 fibroblasts to myoblasts

@article{Lassar1986TransfectionOA,
  title={Transfection of a DNA locus that mediates the conversion of 
 
 
 10T1
 
 2
 
 fibroblasts to myoblasts},
  author={Andrew B. Lassar and Bruce M. Paterson and Harold Weintraub},
  journal={Cell},
  year={1986},
  volume={47},
  pages={649-656}
}

Commitment of mouse fibroblasts to adipocyte differentiation by DNA transfection.

Transfection of a trans-regulatory gene (or genes) from 3T3-F442A or human fat cells into 3T2-C2 cells is sufficient to commit 3T1-C1 cells to adipocyte differentiation.

Effect of cellular determination on oncogenic transformation by chemicals and oncogenes

The presence of as many as six copies of the c-Ha-ras gene per genome did not prevent the formation of striated muscle cells which expressed immunologically detectable muscle-specific myosin and the expression of the determination gene for myogenesis or prevent end-stage myogenic differentiation.

Effect of myogenic determination on tumorigenicity of chemically transformed 10T1/2 cells

Induction of myogenic determination was not sufficient to abolish the tumorigenic phenotype of MCA CI 15C1 cells, but several tumors showed decreased levels of MyoD1 mRNA, suggesting that growth in vivo either selected for or caused decreased determination gene expression.

- 5-5 ’ Azacytidine Enhances Exogenous Gene Expression in Skeletal Muscle

5’ azacytidine enhances the level and the time span of exogenous gene expression in mu scle cells facilitating gene therapy studies, as shown by DNA restriction analysis.
...

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